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The knee is one of the complex and strongest joints in the human body. It plays a significant role in supporting the body’s weight and allows the movement of lower limbs. Also, the movement of the knee joint is essential for sitting, standing, and walking. Any disability to the knee joint can hinder everyday activities. Until date, most of them prefer conservative treatment to relieve knee pain in the form of medications, physical therapy, and surgical intervention for chronic knee conditions.

With numerous advancements happening in the field of orthopedics, stem cell therapy is gaining attention with its advantages over traditional orthopedic treatments. Stem cell therapy helps to reduce knee pain and promotes knee cartilage regeneration & repair. Over the past two decades, numerous research papers have been published regarding the potential of stem cells in knee cartilage regeneration.

The regeneration capacity of stem cells has paved the way for the novel regenerative therapies in the field of orthopedics. The stem cell treatment for the knee repairs the damaged knee cartilage with the help of the patient’s own biological cells. The stem cell procedure can be completed without an incision on the skin. Regenerative stem cell therapy for knee cartilage is the most effective non-surgical treatment option for knee conditions, such as meniscus tear & cartilage damage leading to knee pain and knee arthritis. Also, stem cell therapy stands as an effective alternative to knee replacement surgery.

Understanding the use of stem cells

Stem cells, also known as the master cells, are the specialized cells that can develop into different cell types in the body. Stem cells have a unique potential to repair, regenerate, and restore healthy tissue. This enhances their ability to be used in the treatment of various diseases and medical conditions. Stem cells can differentiate into bone, muscle, cartilage, ligament or tendon. The stem cells secrete a protein called cytokines that plays a significant role in tissue repair.

Stem cells maintain the integrity of the tissue in which they are present. The clinical advantages of bone-marrow-derived stem cells help in the treatment of ligament tear and tendon repair in chronic orthopedic conditions. The application of stem cells in non-surgical orthopedic treatments enables faster regeneration of the cartilage tissue. The cartilage defects can be repaired by a concentrated form of bone-marrow-derived stem cells by administering them into the damaged tissue.

Stem cells for cartilage repair

The joint cartilage promotes the easy movement of the joint surfaces and cushions the bone from friction. Stem cell therapy for knees heals the tissue by controlling the damage and preventing the death of the cartilage tissue.

Stem cell clinical trials for knees is one of the most happening stem cell research in the field of orthopedics. Stem cells enable the regeneration of healthy cartilage tissue and are an effective alternative to knee replacement.

With the promising benefits of stem cells, various clinics across the world are providing stem cell therapy for osteoarthritis. The stem cell treatment for knee osteoarthritis enables the regeneration of healthy cartilage tissue in the damaged part of the knee.

Needle-based approach to treat knee arthritis

Knee arthritis can now be treated with stem cell injections without a need for surgery. Stem cell injection for knee arthritis helps to repair the damaged tissue and regrow the healthy cartilage in the knee. Stem cell therapy for knees involves the collection of stem cells from the bone marrow of the patient. The collected stem cells are concentrated in the laboratory for further clinical purposes.

A stem cell injection contains a concentrated form of autologous stem cells that are collected from the patient’s bone marrow. By using precise-image guided techniques, such as fluoroscopy and ultrasound, the customized concentration of stem cells are injected at the site of injury or damage. In some instances, the stem cell injection is followed by platelet-rich plasma (PRP) therapy, which contains a highly concentrated form of blood platelets. The growth factors from PRP injections repair the damaged cartilage, reduces inflammation in the knee, and helps in rebuilding the knee cartilage. The combination of stem cell therapy and PRP procedure helps to boost the cartilage regeneration.

Stem cell injections to repair knee cartilage not only prevent the further deterioration of the knee cartilage but also protects the healthy tissue surrounding it. With comprehensive research on the use of stem cells for knee joint treatment, it is believed that stem cell therapy works by controlling the inflammation and releasing a protein known as a cytokine, which slows down the cartilage degeneration. This, in turn, reduces the pain in the knee and enables easy mobility. The stem cell injections are administered under complete aseptic precautions using a mist / cold spray and the patient doesn’t have to stay long in the hospital post-treatment. The regeneration of essential cartilage cells post-stem cell injection gradually minimizes the natural deterioration of the knee cartilage tissue.

Regenerative therapy for degenerative knee conditions

Stem cell therapy – Its approach in addressing knee problems

Stem cell therapy is an advanced non-surgical, minimally invasive procedure to treat and prevent various diseases and conditions. It is one of the latest used treatments in the field of orthopedics to treat degenerative conditions. Stem cells allow the regeneration of cartilage tissue, which helps to treat and prevent various orthopedic conditions that are caused by cartilage degeneration.

The stem cells collected from the patient’s bone marrow are used to address knee conditions, such as knee arthritis, meniscus tear, Anterior Cruciate Ligament (ACL) tear, and knee pain. The stem cells are centrifuged and concentrated in the laboratory for further clinical use. Depending on the injury or damage to the knee tissue, the customized concentrations of stem cells are injected percutaneously into the knee.

The stem cells are precisely injected into the area of damage with the help of image-guided techniques, such as fluoroscopy and ultrasound. Additional growth factors in the form of platelet-rich plasma (PRP) therapy are injected to promote tissue regeneration effectively.

Potential benefits of stem cell treatment for knee

The use of stem cells for knee conditions can reduce swelling, ease knee pain, and enable cartilage regeneration, thereby improving the range of motion. Stem cell therapy is a non-surgical treatment that does not even involve an incision of the skin. Stem cell treatment for the knee allows regeneration of tissue without medications and surgical intervention.

The stem cell procedures are the same-day or outpatient protocols that do not require a hospital stay. The stem cell procedures provide faster recovery and require lesser time for rehabilitation. Post-treatment physiotherapy helps in proper regeneration stem cells in the body, which enables faster healing of the knee joint. Unlike conventional treatments or surgery, stem cell treatment for the knee does not result in post-procedure complications, such as infections and other side effects.

Frequently Asked Questions (FAQ)

1. How long does stem cell therapy last for knees?

Stem cells for cartilage repair is an effective treatment option for people suffering from knee arthritis. Once the customized stem cells are injected into the knee, the regeneration of cartilage tissue happens at the target area. A randomized control trial of Regenexx same-day procedure has shown that a patient who received stem cell therapy for knee arthritis can get relief from the pain for up to 5-7 years. The stem cells for cartilage repair enable the regeneration of the new cells at the target site for up to one year after receiving the stem cell injection.

2. Does stem cell therapy for knees work?

Stem cell regenerative therapy for knees is a promising treatment approach that helps to regrow the cartilage in the knee. Cartilage regeneration is essential for the people suffering from various knee conditions, such as arthritis, ligament tear, meniscus tears and other knee conditions. The regeneration potential of stem cells makes them develop into different types of cells in the body. When the stem cells are injected into the damaged tissue of the knee, they begin to regenerative healthy cartilage tissue and prevent further tissue damage in the surrounding area.

3. How much does stem cell therapy for knee cost?

The treatment cost for knee stem cell therapy depends on the type of injury or damage caused to the knee. The treatment cost will be based on the extent of the damage. The average cost of the stem cell treatment will be known at the initial consultation with the doctor once he gets to see your radiology lab reports. Most of the insurance companies do not cover the cost of stem cell therapy.

4. Can stem cells regenerate knee cartilage?

The regeneration capacity of a cartilage tissue reduces with aging. Conventional methods like medications and physical therapy provide symptomatic pain relief, which is temporary. Over the past few years, extensive stem cell research across the world has proved that stem cells aid in cartilage regeneration. The stem cells obtained from the bone marrow are known to have tissue regeneration potential and are efficient in the management of osteoarthritis.

5. Can osteoarthritis be cured by stem cell therapy?

Osteoarthritis is a chronic degenerative disorder that occurs due to a ligament tear or tendon damage. It is a condition that often affects the knee and leads to the deterioration of the knee joint cartilage over time. Stem cell treatment for the knee promotes the regrowth of knee cartilage and also prevents the damage of the surrounding healthy tissue.

6. What are the negative effects of stem cell therapy?

Stem cell infusion helps in the regeneration of tissue in the body. There are no proven adverse effects or side effects of stem cell therapy in orthopedic treatments. However, there are some safety concerns, such as reaction at the site of administration of stem cells and the failure of stem cell regeneration as expected, which is rare.

7. Do stem cell injections help arthritis?

Stem cell injections are helpful to treat arthritis in the knee joints. These injections are delivered directly into the arthritis joints with specialized needles. The bone marrow stem cells that are harvested from the patient’s body are concentrated in the lab and are precisely delivered into the site of cartilage damage. The doctors make use of imaging techniques, such as fluoroscopy and ultrasound, for the precise delivery of stem cells. The stem cells, when injected into the body, initiate the process of regeneration, which give rise to new cells.

8. Can stem cells turn into cancer cells?

Stem cells are known to repair and replace damaged tissue in the body. This regenerative ability of stem cells has helped us from various chronic conditions for which medications have given only symptomatic relief. Not to surprise that stem cells, on the other hand, can be a source of developing cancer. Stem cells differentiate into various cell types and have a longer life than normal cells. The longevity of stem cells can increase the chance of accumulating genetic mutations. Within a very few mutations, a cell can lose control of its multiplication and growth, which can turn to be a source of cancer development.

9. What is the success rate of stem cell therapy for knee conditions?

Over the past few years, a significant number of patients have benefited from stem cell therapy. Stem cells worked well in patients who anticipated regeneration of knee cartilage in case of conditions, such as knee arthritis and a torn meniscus. Also, stem cell therapy helped to improve the range of motion in people who suffered from arthritis of the knee. Many athletes could avoid surgery for a torn meniscus and are highly satisfied with the significant results that they obtained from stem cell therapy.

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 4 reviews



I am a 70+ male who had accepted dibillitating shoulder pain as a given for the rest of my life. 2 surgeons told me that shoulder replacement was my only option and that would not address my arthritis pain.

When I heard about Regenexx and Regen Ortho Sport, I was skeptical to say the least. After much research, I contacted Regen and had an MRI on both shoulders. I spoke with Dr. Movva and he told me the procedure would help me but couldn't guarantee the range of motion I had as a teenager.

I had the procedure in both shoulders and the arthritis pain was gone within 2 weeks. I have full range of motion in both shoulders within 4 months-PAIN FREE!!. Pain no longer wakes me up at night.

The results seem too good to be true but they are true. All the staff made me feel right at home from the beginning - I couldn't ask for a better experience.



This technology is amazing. My knees are really good - no pain. I had them done in February. Have stem cells - please don’t have knee replacements.



Went here on a friend's referral to have stem cells pulled from my back and placed into my knees. The staff is amazing and patient. I had lots of questions and several scheduling issues. Dr. Movva was very gracious as well. I'll update this post 6 months from now to see if I can feel a healing going on.



I had been experiencing severe ankle pain for almost two years. I was barely able to walk 100 feet without having to rest. It was determined that I had several issues, arthritis, ligament damage, and bone spurs. I was hoping for some relief, maybe within a few months. To my amazement, after the fourth day, my pain was almost completely gone! This is day six and I just walked half a mile, PAIN FREE. This result is beyond my wildest expectation. Great job doc !!!