Platelet Lysate (PL) is an even more advanced variation of Platelet Rich Plasma. PRP works by concentrated platelets slowly releasing growth factors over approximately a week. Much like a timed release version of a pill. If you want an immediate release version, with many more growth factors available all at once, you use a platelet lysate (PL). In our experience, while PRP can cause inflammation, PL is very anti-inflammatory and is used more easily around nerves, which is why it is commonly used in our Spine Procedures. Regenexx offers the most advanced platelet lysate available. While many are just beginning to learn about PL, we are in our 3rd generation perfecting this solution on an ongoing basis.